Micromanipulation equipment, United Kingdom, 1994

Micromanipulation equipment, United Kingdom, 1994 Micromanipulation equipment, United Kingdom, 1994 Micromanipulation equipment, United Kingdom, 1994

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Creative Commons LicenseThis image is released under a CC BY-NC-SA 4.0 Licence

Buy this image as a print 

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License this image for commercial use at Science and Society Picture Library

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Creative Commons LicenseThis image is released under a CC BY-NC-SA 4.0 Licence

Buy this image as a print 

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License this image for commercial use at Science and Society Picture Library

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Science Museum Group Collection
© The Board of Trustees of the Science Museum

Science Museum Group Collection
© The Board of Trustees of the Science Museum

Science Museum Group Collection
© The Board of Trustees of the Science Museum

Micromanipulation equipment, used for in vitro fertilization of ovum with sperm, consisting of manipulator, microsyringes and Olympus trinocular microscope, assembled by Research Instruments Limited, England, 1994 (Microinjection-microaspiration syringe & manipulator and micrometer syringe made in Switzerland; Olympus trinocluar microscope made in Japan.)

On 25 July 1978, Louise Brown was born, becoming the first baby conceived and born after IVF treatment. This breakthrough came from years of groundbreaking research by Robert Edwards, Jean Purdy, and Patrick Steptoe. During IVF, eggs are fertilised with sperm outside of the body and then the resulting embryos are transferred to the uterus. Since the 1970s, many innovations have made the IVF process more efficient and effective. In 1980, Edwards, Purdy, and Steptoe reported a success rate of 6%, whereas in 2019, the success rate of IVF treatment in the UK for under 35s was 32%. However, there is a postcode lottery when it comes to receiving IVF treatment on the NHS, and many people have to pay for private treatment. It can also take several cycles of IVF to be successful and can often be mentally and physically challenging.

One of the most important technological innovations has been intracytoplasmic sperm injection (ICSI). For around half of couples who are having trouble conceiving, this is related to the sperm. ICSI was first used clinically in 1992 to help overcome this. It has since become the most common and successful treatment for sperm related infertility. For patients the process is the same as conventional IVF. But in the laboratory a single sperm is injected directly into the egg to fertilise it. This requires incredible precision. With micromanipulators like this, the movement of the joysticks is replicated as tiny movements at the pipette tip where the egg and sperm are held in specially designed needles. This smooths out any shaky hand movements and allows for an impressive degree of accuracy.

Details

Category:
Laboratory Medicine
Object Number:
1995-732
Materials:
metal, plastic and glass
Measurements:
overall: 510 mm x 590 mm x 400 mm,
type:
microscope and micromanipulators
credit:
Research Instruments Limited

Parts

Single Tool-Holder Micromanipulator

Single tool-holder micromanipulator, with axial drive, assembled by Research Instruments Limited, Penryn, Cornwall, England, 1990-95. Used for egg manipulation during the IVF process.

More

On 25 July 1978, Louise Brown was born, becoming the first baby conceived and born after IVF treatment. This breakthrough came from years of groundbreaking research by Robert Edwards, Jean Purdy, and Patrick Steptoe. During IVF, eggs are fertilised with sperm outside of the body and then the resulting embryos are transferred to the uterus. Since the 1970s, many innovations have made the IVF process more efficient and effective. In 1980, Edwards, Purdy, and Steptoe reported a success rate of 6%, whereas in 2019, the success rate of IVF treatment in the UK for under 35s was 32%. However, there is a postcode lottery when it comes to receiving IVF treatment on the NHS, and many people have to pay for private treatment. It can also take several cycles of IVF to be successful and can often be mentally and physically challenging.

One of the most important technological innovations has been intracytoplasmic sperm injection (ICSI). For around half of couples who are having trouble conceiving, this is related to the sperm. ICSI was first used clinically in 1992 to help overcome this. It has since become the most common and successful treatment for sperm related infertility. For patients the process is the same as conventional IVF. But in the laboratory a single sperm is injected directly into the egg to fertilise it. This requires incredible precision. With micromanipulators like this, the movement of the joysticks is replicated as tiny movements at the pipette tip where the egg and sperm are held in specially designed needles. This smooths out any shaky hand movements and allows for an impressive degree of accuracy.

Measurements:
overall: 300 mm x 200 mm x 130 mm,
Materials:
steel (metal) , aluminium (metal) and plastic (unidentified)
Object Number:
1995-732 Pt1
type:
micromanipulators
Image ©
The Board of Trustees of the Science Museum
Axial Drive Micropipette-Holder Micromanipulator

Axial Drive Micropipette-Holder Micromanipulator

Axial drive micropipette-holder micromanipulator, assembled by Research Instruments Limited, Penryn, Cornwall, England, 1990-1995. Used for egg manipulation during the IVF process.

More

On 25 July 1978, Louise Brown was born, becoming the first baby conceived and born after IVF treatment. This breakthrough came from years of groundbreaking research by Robert Edwards, Jean Purdy, and Patrick Steptoe. During IVF, eggs are fertilised with sperm outside of the body and then the resulting embryos are transferred to the uterus. Since the 1970s, many innovations have made the IVF process more efficient and effective. In 1980, Edwards, Purdy, and Steptoe reported a success rate of 6%, whereas in 2019, the success rate of IVF treatment in the UK for under 35s was 32%. However, there is a postcode lottery when it comes to receiving IVF treatment on the NHS, and many people have to pay for private treatment. It can also take several cycles of IVF to be successful and can often be mentally and physically challenging.

One of the most important technological innovations has been intracytoplasmic sperm injection (ICSI). For around half of couples who are having trouble conceiving, this is related to the sperm. ICSI was first used clinically in 1992 to help overcome this. It has since become the most common and successful treatment for sperm related infertility. For patients the process is the same as conventional IVF. But in the laboratory a single sperm is injected directly into the egg to fertilise it. This requires incredible precision. With micromanipulators like this, the movement of the joysticks is replicated as tiny movements at the pipette tip where the egg and sperm are held in specially designed needles. This smooths out any shaky hand movements and allows for an impressive degree of accuracy.

Measurements:
overall: 300 mm x 200 mm x 130 mm,
Materials:
steel (metal) , aluminium (metal) and plastic (unidentified)
Object Number:
1995-732 Pt2
type:
micromanipulators
Screw-actuated Microinjection-microaspiration Syringe and Manipulator

Screw-actuated Microinjection-microaspiration Syringe and Manipulator

Screw-actuated microinjection-microaspiration syringe and manipulator, made by Hamilton Bonaduz AG, Graubünden, Switzerland and assembled by Research Instruments Limited, Penryn, Cornwall, England, 1990-1995. Used for egg manipulation during the IVF process.

More

On 25 July 1978, Louise Brown was born, becoming the first baby conceived and born after IVF treatment. This breakthrough came from years of groundbreaking research by Robert Edwards, Jean Purdy, and Patrick Steptoe. During IVF, eggs are fertilised with sperm outside of the body and then the resulting embryos are transferred to the uterus. Since the 1970s, many innovations have made the IVF process more efficient and effective. In 1980, Edwards, Purdy, and Steptoe reported a success rate of 6%, whereas in 2019, the success rate of IVF treatment in the UK for under 35s was 32%. However, there is a postcode lottery when it comes to receiving IVF treatment on the NHS, and many people have to pay for private treatment. It can also take several cycles of IVF to be successful and can often be mentally and physically challenging.

One of the most important technological innovations has been intracytoplasmic sperm injection (ICSI). For around half of couples who are having trouble conceiving, this is related to the sperm. ICSI was first used clinically in 1992 to help overcome this. It has since become the most common and successful treatment for sperm related infertility. For patients the process is the same as conventional IVF. But in the laboratory a single sperm is injected directly into the egg to fertilise it. This requires incredible precision. With micromanipulators like this, the movement of the joysticks is replicated as tiny movements at the pipette tip where the egg and sperm are held in specially designed needles. This smooths out any shaky hand movements and allows for an impressive degree of accuracy.

Materials:
steel (metal) , aluminium alloy , plastic (unidentified) and glass
Object Number:
1995-732 Pt3
type:
syringe and micromanipulators
Image ©
The Board of Trustees of the Science Museum
Screw-actuated Microinjection-microaspiration Syringe and Manipulator

Screw-actuated Microinjection-microaspiration Syringe and Manipulator

Screw-actuated microinjection-microaspiration syringe and manipulator, made by Hamilton Bonaduz AG, Graubünden, Switzerland and assembled by Research Instruments Limited, Penryn, Cornwall, England, 1990-1995. Used for egg manipulation during the IVF process

More

On 25 July 1978, Louise Brown was born, becoming the first baby conceived and born after IVF treatment. This breakthrough came from years of groundbreaking research by Robert Edwards, Jean Purdy, and Patrick Steptoe. During IVF, eggs are fertilised with sperm outside of the body and then the resulting embryos are transferred to the uterus. Since the 1970s, many innovations have made the IVF process more efficient and effective. In 1980, Edwards, Purdy, and Steptoe reported a success rate of 6%, whereas in 2019, the success rate of IVF treatment in the UK for under 35s was 32%. However, there is a postcode lottery when it comes to receiving IVF treatment on the NHS, and many people have to pay for private treatment. It can also take several cycles of IVF to be successful and can often be mentally and physically challenging.

One of the most important technological innovations has been intracytoplasmic sperm injection (ICSI). For around half of couples who are having trouble conceiving, this is related to the sperm. ICSI was first used clinically in 1992 to help overcome this. It has since become the most common and successful treatment for sperm related infertility. For patients the process is the same as conventional IVF. But in the laboratory a single sperm is injected directly into the egg to fertilise it. This requires incredible precision. With micromanipulators like this, the movement of the joysticks is replicated as tiny movements at the pipette tip where the egg and sperm are held in specially designed needles. This smooths out any shaky hand movements and allows for an impressive degree of accuracy.

Measurements:
overall: 30 mm x 100 mm x 150 mm, .75kg
Materials:
stainless steel and aluminium (metal)
Object Number:
1995-732 Pt4
type:
micromanipulators
Image ©
The Board of Trustees of the Science Museum
'Olympus Routine' Trinocular Inverted Microscope

'Olympus Routine' Trinocular Inverted Microscope

'Olympus Routine', trinocular inverted microscope, with two 15x eyepieces, one A4, 0.1mm objective lens and mechanical stage attachment, made by Olympus, Tokyo, Japan, modified by Research Instruments Limited, Penryn, Cornwall, England, 1990-1995 (see note).

More

On 25 July 1978, Louise Brown was born, becoming the first baby conceived and born after IVF treatment. This breakthrough came from years of groundbreaking research by Robert Edwards, Jean Purdy, and Patrick Steptoe. During IVF, eggs are fertilised with sperm outside of the body and then the resulting embryos are transferred to the uterus. Since the 1970s, many innovations have made the IVF process more efficient and effective. In 1980, Edwards, Purdy, and Steptoe reported a success rate of 6%, whereas in 2019, the success rate of IVF treatment in the UK for under 35s was 32%. However, there is a postcode lottery when it comes to receiving IVF treatment on the NHS, and many people have to pay for private treatment. It can also take several cycles of IVF to be successful and can often be mentally and physically challenging.

One of the most important technological innovations has been intracytoplasmic sperm injection (ICSI). For around half of couples who are having trouble conceiving, this is related to the sperm. ICSI was first used clinically in 1992 to help overcome this. It has since become the most common and successful treatment for sperm related infertility. For patients the process is the same as conventional IVF. But in the laboratory a single sperm is injected directly into the egg to fertilise it. This requires incredible precision. Looking through a microscope like this and using micromanipulators, the movement of the joysticks is replicated as tiny movements at the pipette tip where the egg and sperm are held in specially designed needles. This smooths out any shaky hand movements and allows for an impressive degree of accuracy.

Measurements:
overall: 470 mm x 340 mm x 400 mm,
Materials:
steel (metal) , glass , aluminium alloy and electronic components
Object Number:
1995-732 Pt5
type:
microscope
Replacement needles for IVF machine

Replacement needles for IVF machine

Replacement needles for micromanipulation equipment, used for in vitro fertilization of ovum with sperm, assembled by Research Instruments Limited, Penryn, Cornwall, England, 1990-1995

More

On 25 July 1978, Louise Brown was born, becoming the first baby conceived and born after IVF treatment. This breakthrough came from years of groundbreaking research by Robert Edwards, Jean Purdy, and Patrick Steptoe. During IVF, eggs are fertilised with sperm outside of the body and then the resulting embryos are transferred to the uterus. Since the 1970s, many innovations have made the IVF process more efficient and effective. In 1980, Edwards, Purdy, and Steptoe reported a success rate of 6%, whereas in 2019, the success rate of IVF treatment in the UK for under 35s was 32%. However, there is a postcode lottery when it comes to receiving IVF treatment on the NHS, and many people have to pay for private treatment. It can also take several cycles of IVF to be successful and can often be mentally and physically challenging.

One of the most important technological innovations has been intracytoplasmic sperm injection (ICSI). For around half of couples who are having trouble conceiving, this is related to the sperm. ICSI was first used clinically in 1992 to help overcome this. It has since become the most common and successful treatment for sperm related infertility. For patients the process is the same as conventional IVF. But in the laboratory a single sperm is injected directly into the egg to fertilise it. This requires incredible precision. With micromanipulators like this, the movement of the joysticks is replicated as tiny movements at the pipette tip where the egg and sperm are held in specially designed needles. This smooths out any shaky hand movements and allows for an impressive degree of accuracy.

Measurements:
overall: 510 mm x 590 mm x 400 mm,
Materials:
glass
Object Number:
1995-732 Pt6
type:
needle
Image ©
The Board of Trustees of the Science Museum