Craig counter current distribution apparatus, used at Sir William Dunn School of Pathology, 1940-1960
1940-1960
Craig counter current distribution apparatus
- Made:
- 1940-1960 in unknown
- maker:
- Unknown
Craig counter current distribution apparatus with 70 glass components, used to separate compounds within liquids, used at the Sir William Dunn School of Pathology at Oxford University, 1940-1960
This laboratory apparatus is used to carry out an analytical chemistry technique called counter current distribution, which is used to separate compounds within liquids. It is a technique and piece of apparatus that became crucial to the purification of drugs including penicillin and other antibiotics, antimalarials, as well as hormones and vitamins from the 1940s.
During the Second World war, American biochemist Lyman C. Craig, and Otto Post, a machinist and glassblower, designed the equipment and technique whilst working at the Rockefeller Institute for Medical Research.
This apparatus was used at the Sir William Dunn School of Pathology at Oxford University, and was likely used in research to purify and identify antibiotics during the 1940s and 1950s. Led by Sir Howard Florey, scientists at the institute pioneered the development of penicillin and demonstrated how effective it could be against bacterial infections.
The apparatus worked by means of an ingenious arrangement of glass tubes within a tilting frame. On repeated tilts, shakes, and settling times, heavier liquid parts remained stationary while the lighter parts transferred stepwise from one tube to the next, ultimately isolating pure components in the mixture at the end of the cycle. Some compounds can be separated by a few transfers while others require hundreds of cycles.
Glass components associated with the Craig countercurrent distribution apparatus
Glass components associated with the Craig countercurrent distribution apparatus
Glass components associated with the Craig countercurrent distribution apparatus
Glass component associated with the Craig countercurrent distribution apparatus
Glass components associated with the Craig countercurrent distribution apparatus
Glass components associated with the Craig countercurrent distribution apparatus
Glass component associated with the Craig countercurrent distribution apparatus
Glass component associated with the Craig countercurrent distribution apparatus
Glass component associated with the Craig countercurrent distribution apparatus
Glass component associated with the Craig countercurrent distribution apparatus
Glass component associated with the Craig countercurrent distribution apparatus
1940-1950
Glass component associated with the Craig countercurrent distribution apparatus
1940-1950
Glass component associated with the Craig countercurrent distribution apparatus
1940-1950
Glass component associated with the Craig countercurrent distribution apparatus
1940-1950
Glass component associated with the Craig countercurrent distribution apparatus
1940-1950
Glass component associated with the Craig countercurrent distribution apparatus
1940-1950
Glass component associated with the Craig countercurrent distribution apparatus
1940-1950
Glass component associated with the Craig countercurrent distribution apparatus
1940-1950
Glass component associated with the Craig countercurrent distribution apparatus
1940-1950
Glass component associated with the Craig countercurrent distribution apparatus
1940-1950
Glass component associated with the Craig countercurrent distribution apparatus
1940-1950
Glass component associated with the Craig countercurrent distribution apparatus
1940-1950
Glass component associated with the Craig countercurrent distribution apparatus
1940-1950
Glass component associated with the Craig countercurrent distribution apparatus
1940-1950
See more
Details
- Category:
- Biochemistry
- Object Number:
- 1982-476
- Materials:
- glass
- credit:
- Sir William Dunn School of Pathology
Related Objects
pH meter
Wallchart used to Illustrate Animal Virus Morphology
Latapie mincer
Dickens-simer vessel
Three dimensional electron density map (glass) of turnip yellow mosiac virus
