Two autoradiographs, San Francisco, United States, 1984

Made:
1984 in San Francisco
maker:
Karen Wood

Buy this image as a print 

License this image for commercial use at Science and Society Picture Library

Buy this image as a print 

License this image for commercial use at Science and Society Picture Library

One of two autoradiographs, identifying the human blood factor VIII gene and the mRNA for human blood factor VIII,
Science Museum Group Collection
© The Board of Trustees of the Science Museum

One of two autoradiographs, identifying the human blood factor VIII gene and the mRNA for human blood factor VIII,
Science Museum Group Collection
© The Board of Trustees of the Science Museum

2 autoradiographs, identifying the human blood factor VIII gene and the mRNA for human blood factor VIII, prepared by Karen Wood at Genentech

An autoradiograph is used in decoding the structure of such key chemicals in the human body as DNA and RNA. One plate shows the human blood Factor VIII gene, which is involved in blood clotting. The other plate shows the messenger RNA (mRNA) for Factor VIII.

This work was particularly important as it could be used to help produce Factor VIII from genetically modified bacteria rather than from human blood. This product could be used to treat haemophilia and von Willebrand’s disease, which are both blood-clotting disorders. By using Factor VIII from bacteria rather than from human blood any risk of transmitting such blood-borne infections as AIDS and Hepatitis is eliminated. The work was conducted by the Genentech company based in South San Francisco, an area in which AIDS was unusually common in the 1980s.

Related people

Details

Category:
Biochemistry
Object Number:
1994-674
type:
autoradiograph
taxonomy:
  • visual and verbal communication
  • photograph
  • x-ray photograph
credit:
Genentech Inc.

Cite this page

Rights

We encourage the use and reuse of our collection data.


Data in the title, made, maker and details fields are released under Creative Commons Zero


Descriptions and all other text content are licensed under a Creative Commons Attribution 4.0 licence

Using our data

Download

Download catalogue entry as json

View manifest in IIIF viewer

Add to Animal Crossing Art Generator

Download manifest IIIF

Our records are constantly being enhanced and improved, but please note that we cannot guarantee the accuracy of any information shown on this website.