'Genesis 2000' DNA Sequencer, England, 1988

Made:
1988 in England
Left hand side: 1996-310, Dupont Genesis 2000 Sequencer, used together with 1995-1678 to investigate structure-function Left hand side: 1996-310, Dupont Genesis 2000 Sequencer, used together with 1995-1678 to investigate structure-function

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Left hand side: 1996-310, Dupont Genesis 2000 Sequencer, used together with 1995-1678 to investigate structure-function
Science Museum Group Collection
© The Board of Trustees of the Science Museum

Left hand side: 1996-310, Dupont Genesis 2000 Sequencer, used together with 1995-1678 to investigate structure-function
Science Museum Group Collection
© The Board of Trustees of the Science Museum

Dupont Genesis 2000 Sequencer, used together with 1995-1678 to investigate structure-function relationships in enzymes such as papaine

The Institute of Food Research investigated the protein engineering cycle. It wanted to examine the structure/function relationships in enzymes such as papain. This sequencer (seen on the left) together with the DuPont Coder 300 DNA Synthesiser was used in the investigation. The ‘Genesis 2000’ used the analytical approach developed at MIT by Walter Gilbert. It was commercialised by large chemical company DuPont. The effects of site-specific mutations were predicted using the synthesiser. They were verified in a cloned specimen using the sequencer.

Details

Category:
Biochemistry
Object Number:
1996-310
Materials:
metal and plastic
type:
protein sequencer
credit:
Institute of Food Research