477A Protein Sequencer
The 477A protein sequencer was used in biotechnical research during the 1980s. It analysed proteins and peptides using a technique derived from the original discoveries of Swedish biochemist Pehr Edman (1916-77) in the 1950s. Edman developed a method, known as Edman degradation, to determine the sequence of amino acids in proteins. Amino acids are the building blocks of proteins. This machine was made by Applied Biosystems in California. Machines such as this, and its successors, have been essential to biotechnology laboratories. They have been used in the genetic modification of foods, animal cloning and genetic fingerprinting.
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- Applied Biosystems Limited
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