Berthold 280 paper strip scanner, modified mid-1980s. A Radioactivity Aperstrip scanner customised by the Oxford University Glycobiology Unit for use in sugar sequencing experiments.
Used for paper chromatography, this machine was modified to become a piece of equipment known as a radioactivity paperstrip scanner. The results were printed out from the paper-fed panel on the left. The University of Oxford Glycobiology Unit carried out the modification in order to perform experiments to determine the sequence of polysaccharides. These are the huge sugars which are found attached to proteins, for instance on the surface of cells. The polysaccharides on cell surfaces can differ between people and over time, and can predispose for immune conditions such as arthritis.
The apparatus was donated to the Science Museum’s collections by the Department of Biochemistry at the University of Oxford. The group under Professor Raymond Dwek pioneered methods of automated analysis of these sugar groups. Their work underpinned Oxford’s first commercial spin-off company, Oxford GlycoSystems, in which the University kept a shareholding. Professor Dwek himself coined the word ‘glycobiology’ in 1988.
- Object Number:
- chromatography equipment
- Oxford University, Dept. of Biochemistry
Cite this page
We encourage the use and reuse of our collection data.
Data in the title, made, maker and details fields are released under Creative Commons Zero
Descriptions and all other text content are licensed under a Creative Commons Attribution 4.0 licence
Download catalogue entry as json
View manifest in IIIF viewer
Download manifest IIIF
Our records are constantly being enhanced and improved, but please note that we cannot guarantee the accuracy of any information shown on this website.