Electrofusion apparatus used to create Dolly the sheep, Scotland, 1996

Made:
1996-1998 in United Kingdom
maker:
Unknown
Electrofusion apparatus used to create Dolly, the cloned sheep.  Front 3/4 view of whole object against graduated grey

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Electrofusion apparatus used to create Dolly, the cloned sheep. Front 3/4 view of whole object against graduated grey
Science Museum Group Collection
© The Board of Trustees of the Science Museum

Science Museum Group
The Board of Trustees of the Science Museum

Electrofusion apparatus used by the Roslin Institute to create Dolly, the first cloned sheep, at Roslin, Midlothian, Scotland, 1996-1998 (see note).

Dolly the sheep was the first mammal cloned from an adult cell. The cloning process was jump-started using a pulse from this electrofusion machine at the Roslin Institute in Scotland. Dolly was created by taking the DNA from an adult sheep’s mammary cell which was then inserted into a DNA-free egg. An electrical pulse from this machine stimulated the egg and the donor DNA into behaving like a newly fertilised egg. The egg developed into a cluster of cells (a blastocyst) which was then implanted into a surrogate mother sheep.

Dolly was born in 1996. She later gave birth to a number of lambs. The name ‘Dolly’ was inspired by country and western singer, Dolly Parton.

Details

Category:
Biotechnology
Object Number:
1998-797
Materials:
aluminium (metal), copper (metal), glass, paper (fibre product), plastic (unidentified) and steel (metal)
type:
electrofusion apparatus
credit:
Roslin Institute