Poster for the film 'O Brother Where Art Thou?', 2000.

'O Brother, Where Art Thou?' is a 2000 crime comedy-drama written, produced, and directed by Joel and Ethan Coen, and featuring George Clooney, John Turturro, and Tim Blake Nelson, with John Goodman, Holly Hunter, and Charles Durning in supporting roles.

The film is set in 1937 rural Mississippi during the Great Depression. Its story is a modern satire loosely based on Homer's epic poem The Odyssey that incorporates mythology from the American South. The title of the film is a reference to the Preston Sturges 1941 film 'Sullivan's Travels', in which the protagonist is a director who wants to film O Brother, Where Art Thou?, a fictional book about the Great Depression.

'O Brother Where Art Thou?' was the first film to use digital color correction (or colour grading). Cinematographer Roger Deakins stated, "Ethan and Joel favored a dry, dusty Delta look with golden sunsets. They wanted it to look like an old hand-tinted picture, with the intensity of colors dictated by the scene and natural skin tones that were all shades of the rainbow." Initially the crew tried to perform the color correction using a physical process, however after several tries with various chemical processes proved unsatisfactory, it became necessary to perform the process digitally.