Paperwork from Oxford COVID-19 vaccine trial

Black clipboard with COV002 Screening packs approved document list (May – July 2020), 5 sides of COV002 blood sample collection table V4.0, 3rd July 2020 (based on protocol V8.2 22 June 2020), graphic showing 365 day timeline for consent, blood tests, vaccination doses, e-diaries, and weekly swab testing for participants aged over 18-55 years Group 11 two doses, graphic showing 365 day timeline for consent, blood tests, vaccination doses, e-diaries, and weekly swab testing for participants aged over 56-69 years Group 9 two doses, graphic showing 365 day timeline for consent, blood tests, vaccination doses, e-diaries, and weekly swab testing for participants aged over 70 years Group 10 two doses, graphic showing 365 day timeline for consent, blood tests, vaccination doses, pregnancy tests, e-diaries, and weekly swab testing for participants aged over 18 years Group 5d two doses, 15 page Participant Information Sheet ‘Investigating a Vaccine Against COVID-19) for people aged 18-55 years, V9.0, 20 July 2020, 15 page Participant Information Sheet ‘Investigating a Vaccine Against COVID-19) for people aged 56-69 years, V9.0, 20 July 2020, used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

Testing any new vaccine or medicine relies on healthy volunteers from every age range to come forward. Oxford’s COVID-19 vaccine trials recruited people from all over the United Kingdom. To help speed up the process but maintain safety controls, vaccine developers were allowed to run parts of the trial simultaneously. Known as COV001, phase 1-2 trial involved 1112 participants and COV002, phase 2-3, involved over 12000 adults.

Volunteers are given a health check including blood tests, to screen for health conditions and any immune response to COVID-19. Each person is taken through an informed consent form, ensuring they understand what the trial is and what the risks involved are. Once confirmed in the trial, the volunteer would be randomly assigned to either receive the Oxford COVID-19 vaccine or a meningitis vaccine – which acted as a control. Some minor side effects such as a sore arm, headache and fever were expected from the COVID-19 vaccine. Those in the control group had to be given something that would cause similar side effects, ensuring no-one could work out which group they were in, until the end of the trial.

Socially distanced ‘trial huts’ were built at the CCVTM’s main trial site at the Churchill Hospital, Oxford. Volunteers visited on two occasions for their vaccine doses and then for regular blood tests over the course of a year to see how well the vaccine was working. When blood samples (serum) were taken from volunteers, they were centrifuged or spun and separated into smaller pots (cryovials). Holders and pipettes are used to transfer the serum and the cells after the sample has been centrifuged. Moving samples around was also done in accordance with strict protocols to ensure the integrity of the samples. QR codes were used to track them, and temperature monitors used to ensure they remained at a testable temperature.

Volunteers were also asked to take weekly COVID-19 swab tests to assess who was infected with COVID-19, even if they had no symptoms. Each volunteer was given a kit including an emergency contact card, and a digital thermometer and a paper ruler to monitor their reaction.

Details

Category:
Public Health & Hygiene
Object Number:
2022-1106
Materials:
metal, paper and plastic
Measurements:
overall: 310 mm x 240 mm x 20 mm,
type:
paperwork

Parts

Black clipboard used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

Clipboard from the Oxford COVID-19 Vaccine Trial

Black clipboard used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

More

Testing any new vaccine or medicine relies on healthy volunteers from every age range to come forward. Oxford’s COVID-19 vaccine trials recruited people from all over the United Kingdom. To help speed up the process but maintain safety controls, vaccine developers were allowed to run parts of the trial simultaneously. Known as COV001, phase 1-2 trial involved 1112 participants and COV002, phase 2-3, involved over 12000 adults.

Volunteers are given a health check including blood tests, to screen for health conditions and any immune response to COVID-19. Each person is taken through an informed consent form, ensuring they understand what the trial is and what the risks involved are. Once confirmed in the trial, the volunteer would be randomly assigned to either receive the Oxford COVID-19 vaccine or a meningitis vaccine – which acted as a control. Some minor side effects such as a sore arm, headache and fever were expected from the COVID-19 vaccine. Those in the control group had to be given something that would cause similar side effects, ensuring no-one could work out which group they were in, until the end of the trial.

Socially distanced ‘trial huts’ were built at the CCVTM’s main trial site at the Churchill Hospital, Oxford. Volunteers visited on two occasions for their vaccine doses and then for regular blood tests over the course of a year to see how well the vaccine was working. When blood samples (serum) were taken from volunteers, they were centrifuged or spun and separated into smaller pots (cryovials). Holders and pipettes are used to transfer the serum and the cells after the sample has been centrifuged. Moving samples around was also done in accordance with strict protocols to ensure the integrity of the samples. QR codes were used to track them, and temperature monitors used to ensure they remained at a testable temperature.

Volunteers were also asked to take weekly COVID-19 swab tests to assess who was infected with COVID-19, even if they had no symptoms. Each volunteer was given a kit including an emergency contact card, and a digital thermometer and a paper ruler to monitor their reaction.

Measurements:
overall: 310 mm x 240 mm x 20 mm,
Materials:
metal and plastic
Object Number:
2022-1106/1
type:
paperwork
COV002 Screening packs approved document list (May – July 2020) in plastic wallet used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

Paperwork from Oxford COVID-19 vaccine trial

COV002 Screening packs approved document list (May – July 2020) in plastic wallet used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

More

Testing any new vaccine or medicine relies on healthy volunteers from every age range to come forward. Oxford’s COVID-19 vaccine trials recruited people from all over the United Kingdom. To help speed up the process but maintain safety controls, vaccine developers were allowed to run parts of the trial simultaneously. Known as COV001, phase 1-2 trial involved 1112 participants and COV002, phase 2-3, involved over 12000 adults.

Volunteers are given a health check including blood tests, to screen for health conditions and any immune response to COVID-19. Each person is taken through an informed consent form, ensuring they understand what the trial is and what the risks involved are. Once confirmed in the trial, the volunteer would be randomly assigned to either receive the Oxford COVID-19 vaccine or a meningitis vaccine – which acted as a control. Some minor side effects such as a sore arm, headache and fever were expected from the COVID-19 vaccine. Those in the control group had to be given something that would cause similar side effects, ensuring no-one could work out which group they were in, until the end of the trial.

Socially distanced ‘trial huts’ were built at the CCVTM’s main trial site at the Churchill Hospital, Oxford. Volunteers visited on two occasions for their vaccine doses and then for regular blood tests over the course of a year to see how well the vaccine was working. When blood samples (serum) were taken from volunteers, they were centrifuged or spun and separated into smaller pots (cryovials). Holders and pipettes are used to transfer the serum and the cells after the sample has been centrifuged. Moving samples around was also done in accordance with strict protocols to ensure the integrity of the samples. QR codes were used to track them, and temperature monitors used to ensure they remained at a testable temperature.

Volunteers were also asked to take weekly COVID-19 swab tests to assess who was infected with COVID-19, even if they had no symptoms. Each volunteer was given a kit including an emergency contact card, and a digital thermometer and a paper ruler to monitor their reaction.

Measurements:
overall: 310 mm x 240 mm x 20 mm,
Materials:
paper and plastic
Object Number:
2022-1106/2
type:
paperwork
3 sheets (5 sides) of COV002 blood sample collection table V4.0, 3rd July 2020 (based on protocol V8.2 22 June 2020), in Office Depot plastic wallet used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

COV002 blood sample collection tables from Oxford COVID-19 vaccine trial

3 sheets (5 sides) of COV002 blood sample collection table V4.0, 3rd July 2020 (based on protocol V8.2 22 June 2020), in Office Depot plastic wallet used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

More

Testing any new vaccine or medicine relies on healthy volunteers from every age range to come forward. Oxford’s COVID-19 vaccine trials recruited people from all over the United Kingdom. To help speed up the process but maintain safety controls, vaccine developers were allowed to run parts of the trial simultaneously. Known as COV001, phase 1-2 trial involved 1112 participants and COV002, phase 2-3, involved over 12000 adults.

Volunteers are given a health check including blood tests, to screen for health conditions and any immune response to COVID-19. Each person is taken through an informed consent form, ensuring they understand what the trial is and what the risks involved are. Once confirmed in the trial, the volunteer would be randomly assigned to either receive the Oxford COVID-19 vaccine or a meningitis vaccine – which acted as a control. Some minor side effects such as a sore arm, headache and fever were expected from the COVID-19 vaccine. Those in the control group had to be given something that would cause similar side effects, ensuring no-one could work out which group they were in, until the end of the trial.

Socially distanced ‘trial huts’ were built at the CCVTM’s main trial site at the Churchill Hospital, Oxford. Volunteers visited on two occasions for their vaccine doses and then for regular blood tests over the course of a year to see how well the vaccine was working. When blood samples (serum) were taken from volunteers, they were centrifuged or spun and separated into smaller pots (cryovials). Holders and pipettes are used to transfer the serum and the cells after the sample has been centrifuged. Moving samples around was also done in accordance with strict protocols to ensure the integrity of the samples. QR codes were used to track them, and temperature monitors used to ensure they remained at a testable temperature.

Volunteers were also asked to take weekly COVID-19 swab tests to assess who was infected with COVID-19, even if they had no symptoms. Each volunteer was given a kit including an emergency contact card, and a digital thermometer and a paper ruler to monitor their reaction.

Measurements:
overall: 310 mm x 240 mm x 20 mm,
Materials:
paper and plastic
Object Number:
2022-1106/3
type:
paperwork
Graphic showing 365 day timeline for consent, blood tests, vaccination doses, e-diaries, and weekly swab testing for participants aged over 18-55 years Group 11 two doses, in a plastic wallet, used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

Paperwork from Oxford Vaccine Trial

Graphic showing 365 day timeline for consent, blood tests, vaccination doses, e-diaries, and weekly swab testing for participants aged over 18-55 years Group 11 two doses, in a plastic wallet, used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

More

Testing any new vaccine or medicine relies on healthy volunteers from every age range to come forward. Oxford’s COVID-19 vaccine trials recruited people from all over the United Kingdom. To help speed up the process but maintain safety controls, vaccine developers were allowed to run parts of the trial simultaneously. Known as COV001, phase 1-2 trial involved 1112 participants and COV002, phase 2-3, involved over 12000 adults.

Volunteers are given a health check including blood tests, to screen for health conditions and any immune response to COVID-19. Each person is taken through an informed consent form, ensuring they understand what the trial is and what the risks involved are. Once confirmed in the trial, the volunteer would be randomly assigned to either receive the Oxford COVID-19 vaccine or a meningitis vaccine – which acted as a control. Some minor side effects such as a sore arm, headache and fever were expected from the COVID-19 vaccine. Those in the control group had to be given something that would cause similar side effects, ensuring no-one could work out which group they were in, until the end of the trial.

Socially distanced ‘trial huts’ were built at the CCVTM’s main trial site at the Churchill Hospital, Oxford. Volunteers visited on two occasions for their vaccine doses and then for regular blood tests over the course of a year to see how well the vaccine was working. When blood samples (serum) were taken from volunteers, they were centrifuged or spun and separated into smaller pots (cryovials). Holders and pipettes are used to transfer the serum and the cells after the sample has been centrifuged. Moving samples around was also done in accordance with strict protocols to ensure the integrity of the samples. QR codes were used to track them, and temperature monitors used to ensure they remained at a testable temperature.

Volunteers were also asked to take weekly COVID-19 swab tests to assess who was infected with COVID-19, even if they had no symptoms. Each volunteer was given a kit including an emergency contact card, and a digital thermometer and a paper ruler to monitor their reaction.

Measurements:
overall: 310 mm x 240 mm x 20 mm,
Materials:
metal , paper and plastic
Object Number:
2022-1106/4
type:
paperwork
Graphic showing 365 day timeline for consent, blood tests, vaccination doses, e-diaries, and weekly swab testing for participants aged 56-69years Group 9 two doses, in a plastic wallet, used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

Paperwork from Oxford Vaccine Trial

Graphic showing 365 day timeline for consent, blood tests, vaccination doses, e-diaries, and weekly swab testing for participants aged 56-69years Group 9 two doses, in a plastic wallet, used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

More

Testing any new vaccine or medicine relies on healthy volunteers from every age range to come forward. Oxford’s COVID-19 vaccine trials recruited people from all over the United Kingdom. To help speed up the process but maintain safety controls, vaccine developers were allowed to run parts of the trial simultaneously. Known as COV001, phase 1-2 trial involved 1112 participants and COV002, phase 2-3, involved over 12000 adults.

Volunteers are given a health check including blood tests, to screen for health conditions and any immune response to COVID-19. Each person is taken through an informed consent form, ensuring they understand what the trial is and what the risks involved are. Once confirmed in the trial, the volunteer would be randomly assigned to either receive the Oxford COVID-19 vaccine or a meningitis vaccine – which acted as a control. Some minor side effects such as a sore arm, headache and fever were expected from the COVID-19 vaccine. Those in the control group had to be given something that would cause similar side effects, ensuring no-one could work out which group they were in, until the end of the trial.

Socially distanced ‘trial huts’ were built at the CCVTM’s main trial site at the Churchill Hospital, Oxford. Volunteers visited on two occasions for their vaccine doses and then for regular blood tests over the course of a year to see how well the vaccine was working. When blood samples (serum) were taken from volunteers, they were centrifuged or spun and separated into smaller pots (cryovials). Holders and pipettes are used to transfer the serum and the cells after the sample has been centrifuged. Moving samples around was also done in accordance with strict protocols to ensure the integrity of the samples. QR codes were used to track them, and temperature monitors used to ensure they remained at a testable temperature.

Volunteers were also asked to take weekly COVID-19 swab tests to assess who was infected with COVID-19, even if they had no symptoms. Each volunteer was given a kit including an emergency contact card, and a digital thermometer and a paper ruler to monitor their reaction.

Measurements:
overall: 310 mm x 240 mm x 20 mm,
Materials:
metal , paper and plastic
Object Number:
2022-1106/5
type:
paperwork
15 page Participant Information Sheet ‘Investigating a Vaccine Against COVID-19) for people aged 18-55 years, V9.0, 20 July 2020, in plastic wallets, used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

Paperwork from Oxford Vaccine Trial

15 page Participant Information Sheet ‘Investigating a Vaccine Against COVID-19) for people aged 18-55 years, V9.0, 20 July 2020, in plastic wallets, used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

More

Testing any new vaccine or medicine relies on healthy volunteers from every age range to come forward. Oxford’s COVID-19 vaccine trials recruited people from all over the United Kingdom. To help speed up the process but maintain safety controls, vaccine developers were allowed to run parts of the trial simultaneously. Known as COV001, phase 1-2 trial involved 1112 participants and COV002, phase 2-3, involved over 12000 adults.

Volunteers are given a health check including blood tests, to screen for health conditions and any immune response to COVID-19. Each person is taken through an informed consent form, ensuring they understand what the trial is and what the risks involved are. Once confirmed in the trial, the volunteer would be randomly assigned to either receive the Oxford COVID-19 vaccine or a meningitis vaccine – which acted as a control. Some minor side effects such as a sore arm, headache and fever were expected from the COVID-19 vaccine. Those in the control group had to be given something that would cause similar side effects, ensuring no-one could work out which group they were in, until the end of the trial.

Socially distanced ‘trial huts’ were built at the CCVTM’s main trial site at the Churchill Hospital, Oxford. Volunteers visited on two occasions for their vaccine doses and then for regular blood tests over the course of a year to see how well the vaccine was working. When blood samples (serum) were taken from volunteers, they were centrifuged or spun and separated into smaller pots (cryovials). Holders and pipettes are used to transfer the serum and the cells after the sample has been centrifuged. Moving samples around was also done in accordance with strict protocols to ensure the integrity of the samples. QR codes were used to track them, and temperature monitors used to ensure they remained at a testable temperature.

Volunteers were also asked to take weekly COVID-19 swab tests to assess who was infected with COVID-19, even if they had no symptoms. Each volunteer was given a kit including an emergency contact card, and a digital thermometer and a paper ruler to monitor their reaction.

Measurements:
overall: 310 mm x 240 mm x 20 mm,
Materials:
paper and plastic
Object Number:
2022-1106/6
type:
paperwork
Graphic showing 365 day timeline for consent, blood tests, vaccination doses, e-diaries, and weekly swab testing for participants aged over 70 years Group 10 two doses, in a plastic wallet, used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

Paperwork from Oxford Vaccine Trial

Graphic showing 365 day timeline for consent, blood tests, vaccination doses, e-diaries, and weekly swab testing for participants aged over 70 years Group 10 two doses, in a plastic wallet, used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

More

Testing any new vaccine or medicine relies on healthy volunteers from every age range to come forward. Oxford’s COVID-19 vaccine trials recruited people from all over the United Kingdom. To help speed up the process but maintain safety controls, vaccine developers were allowed to run parts of the trial simultaneously. Known as COV001, phase 1-2 trial involved 1112 participants and COV002, phase 2-3, involved over 12000 adults.

Volunteers are given a health check including blood tests, to screen for health conditions and any immune response to COVID-19. Each person is taken through an informed consent form, ensuring they understand what the trial is and what the risks involved are. Once confirmed in the trial, the volunteer would be randomly assigned to either receive the Oxford COVID-19 vaccine or a meningitis vaccine – which acted as a control. Some minor side effects such as a sore arm, headache and fever were expected from the COVID-19 vaccine. Those in the control group had to be given something that would cause similar side effects, ensuring no-one could work out which group they were in, until the end of the trial.

Socially distanced ‘trial huts’ were built at the CCVTM’s main trial site at the Churchill Hospital, Oxford. Volunteers visited on two occasions for their vaccine doses and then for regular blood tests over the course of a year to see how well the vaccine was working. When blood samples (serum) were taken from volunteers, they were centrifuged or spun and separated into smaller pots (cryovials). Holders and pipettes are used to transfer the serum and the cells after the sample has been centrifuged. Moving samples around was also done in accordance with strict protocols to ensure the integrity of the samples. QR codes were used to track them, and temperature monitors used to ensure they remained at a testable temperature.

Volunteers were also asked to take weekly COVID-19 swab tests to assess who was infected with COVID-19, even if they had no symptoms. Each volunteer was given a kit including an emergency contact card, and a digital thermometer and a paper ruler to monitor their reaction.

Measurements:
overall: 310 mm x 240 mm x 20 mm,
Materials:
metal , paper and plastic
Object Number:
2022-1106/7
type:
paperwork
Graphic showing 365 day timeline for consent, blood tests, vaccination doses, pregnancy tests, e-diaries, and weekly swab testing for participants aged over 18 years Group 5d two doses, in a plastic wallet, used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

Paperwork from Oxford Vaccine Trial

Graphic showing 365 day timeline for consent, blood tests, vaccination doses, pregnancy tests, e-diaries, and weekly swab testing for participants aged over 18 years Group 5d two doses, in a plastic wallet, used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

More

Testing any new vaccine or medicine relies on healthy volunteers from every age range to come forward. Oxford’s COVID-19 vaccine trials recruited people from all over the United Kingdom. To help speed up the process but maintain safety controls, vaccine developers were allowed to run parts of the trial simultaneously. Known as COV001, phase 1-2 trial involved 1112 participants and COV002, phase 2-3, involved over 12000 adults.

Volunteers are given a health check including blood tests, to screen for health conditions and any immune response to COVID-19. Each person is taken through an informed consent form, ensuring they understand what the trial is and what the risks involved are. Once confirmed in the trial, the volunteer would be randomly assigned to either receive the Oxford COVID-19 vaccine or a meningitis vaccine – which acted as a control. Some minor side effects such as a sore arm, headache and fever were expected from the COVID-19 vaccine. Those in the control group had to be given something that would cause similar side effects, ensuring no-one could work out which group they were in, until the end of the trial.

Socially distanced ‘trial huts’ were built at the CCVTM’s main trial site at the Churchill Hospital, Oxford. Volunteers visited on two occasions for their vaccine doses and then for regular blood tests over the course of a year to see how well the vaccine was working. When blood samples (serum) were taken from volunteers, they were centrifuged or spun and separated into smaller pots (cryovials). Holders and pipettes are used to transfer the serum and the cells after the sample has been centrifuged. Moving samples around was also done in accordance with strict protocols to ensure the integrity of the samples. QR codes were used to track them, and temperature monitors used to ensure they remained at a testable temperature.

Volunteers were also asked to take weekly COVID-19 swab tests to assess who was infected with COVID-19, even if they had no symptoms. Each volunteer was given a kit including an emergency contact card, and a digital thermometer and a paper ruler to monitor their reaction.

Measurements:
overall: 310 mm x 240 mm x 20 mm,
Materials:
metal , paper and plastic
Object Number:
2022-1106/8
type:
paperwork
15 page Participant Information Sheet ‘Investigating a Vaccine Against COVID-19) for people aged 18-55 years, V9.0, 20 July 2020, in plastic wallets, used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

Paperwork from Oxford Vaccine Trial

15 page Participant Information Sheet ‘Investigating a Vaccine Against COVID-19) for people aged 18-55 years, V9.0, 20 July 2020, in plastic wallets, used during the clinical trials of the ChAdOx1 nCoV-19, Oxford/AstraZeneca COVID-19 vaccine by the Oxford Vaccine Group, the Jenner Institute and the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM)

More

Testing any new vaccine or medicine relies on healthy volunteers from every age range to come forward. Oxford’s COVID-19 vaccine trials recruited people from all over the United Kingdom. To help speed up the process but maintain safety controls, vaccine developers were allowed to run parts of the trial simultaneously. Known as COV001, phase 1-2 trial involved 1112 participants and COV002, phase 2-3, involved over 12000 adults.

Volunteers are given a health check including blood tests, to screen for health conditions and any immune response to COVID-19. Each person is taken through an informed consent form, ensuring they understand what the trial is and what the risks involved are. Once confirmed in the trial, the volunteer would be randomly assigned to either receive the Oxford COVID-19 vaccine or a meningitis vaccine – which acted as a control. Some minor side effects such as a sore arm, headache and fever were expected from the COVID-19 vaccine. Those in the control group had to be given something that would cause similar side effects, ensuring no-one could work out which group they were in, until the end of the trial.

Socially distanced ‘trial huts’ were built at the CCVTM’s main trial site at the Churchill Hospital, Oxford. Volunteers visited on two occasions for their vaccine doses and then for regular blood tests over the course of a year to see how well the vaccine was working. When blood samples (serum) were taken from volunteers, they were centrifuged or spun and separated into smaller pots (cryovials). Holders and pipettes are used to transfer the serum and the cells after the sample has been centrifuged. Moving samples around was also done in accordance with strict protocols to ensure the integrity of the samples. QR codes were used to track them, and temperature monitors used to ensure they remained at a testable temperature.

Volunteers were also asked to take weekly COVID-19 swab tests to assess who was infected with COVID-19, even if they had no symptoms. Each volunteer was given a kit including an emergency contact card, and a digital thermometer and a paper ruler to monitor their reaction.

Measurements:
overall: 310 mm x 240 mm x 20 mm,
Materials:
metal , paper and plastic
Object Number:
2022-1106/9
type:
paperwork