1887 - Wilhelm & Karl Christian Scheerer, brothers-in-law of Gottfried Jetter, join the company as partners; company is renamed Jetter & Scheerer;

1889 - Aesculap registered trademark design established: stylised staff of Aesculapius, with S shaped snake around staff, surmounted with a crown for Jetter & Scheerer; first branch office opened in Berlin.

1893 - branches opened in New York with London, Paris, Constantinople, Buenos Aires and Tokyo shortly after;

1895 - incorporated as Aktiengesellschaft für Feinmechanik vormals Jetter & Scheerer;

1898 - new factory in Tuttlingen (designed by industrial architect Philipp Jakob Manz);

1900 - Carl Braun (1869-1929) takes over the B Braun company from father Bernhard Braun; AESCULAP registered as a trademark;

1904 - Wilhelm Scheerer leaves Aesculap and Karl Christian Scheerer becomes sole managing director;

1908 - absorbable suture material (catgut) manufactured from sheep intestines using Kuhn´s method (in Melsungen);

1904 - medico-mechanical workshop at B Braun begins manufacturing splints for surgery, simple extensions and blood pressure measuring devices;

1925 - B Braun establishes first foreign production in Milan, Italy;

1929 - Otto Braun (1904-1986) takes over management of B Braun;

1932 - Fritz & Hans Scheerer take over Aesculap from Karl Christian Scheerer;

1935 - production of Synthofil A, a non-absorbable synthetic suture material, begun by B Braun; Aesculap invents the first surgical electric motor;

1949 - B Braun develops new nylon surgical suture material Supramid-Braun;

1951 - mechanical injection pump for continuous infusions launched;

1953 - infusion devices made of glass produced

1956 - infusion devices made of plastic produced

1960 - B Braun develops preparations for modern bone surgery for osteogenesis (Kiel bone grafts);

1962 - Braunüle®, first one-piece cannula for continuous infusion, released; Lipofundin®, first infusable fat emulsion, launched;

1969 - Aesculap renamed Aesculap-Werke Aktiengesellschaft vormals Jetter und Scheerer;

1971 - Aesculap develops new products for cardiovascular surgery, arthroscopy and microsurgery, as well as hip joint protheses; B Braun transformed into B. Braun Melsungen AG a stock corporation;

1972 - Aesculap production site in Penang, Malaysia;

1973 - B. Braun constructs production site for single use medical products at Escholzmatt, Switzerland, in cooperation with SSC Steril Catgut Gesellschaft in Neuhaus/Schaffhausen;

1976 - B. Braun acquires a controlling interest in Aesculap AG and 80 percent interest of Laboratoires Bruneau & Cie, Boulogne/Paris;

1979 - B. Braun of America established with Burron Medical Inc., Bethlehem, United States;

1980 - manufacturing company in Penang, Malaysia;

1992 - after a co-operation period Aesculap becomes majority shareholder of CHIFA Sp.Z o.o.Nowy Tomysl, Poland, a supplier of surgical instruments;

1997 - McGaw, Inc., California, United States acquired; Ecoflac® plus introduced, an innovative container for infusion solutions combining the advantages of glass and plastic bottles;

1998 - Aesculap AG & Co KG is incorporated into the B. Braun Group as the Aesculap Division;

1999 - new factory facility in Tuttlingen, Germany; B. Braun Medical Ltd has new corporate headquarters in Sheffield, England;

2000 - production site for IV-sets in Ponda/Goa, India; B. Braun Biotech sold off to concentrate on healthcare; alliance between B. Braun and Paul Hartmann AG;

2001 - new pharmaceutical factory in Melsungen, Germany; Europa Building at the Pfieffewiesen Facility;

2004 - acquisition of Saxonia GmbH in Radeberg, Germany (production of dialyzers);

2008 - B. Braun acquires Gematek in Twer, Russia;