1885 - Abel Besins founds Laboratoires Besins. 1965 - Laboratoires Besins acquires Laboratoires Iscovesco, forming Laboratoires Besins Iscovesco. 1971 - commences transdermal hormone therapy, with 'Progestogel'. 1980-1999 - produce 'Oestrogel' and later 'Androgel'.