Quekett's work as a histologist, both practical and literary, was original and prolific. His Practical Treatise on the Use of the Microscope (1848) was the first such work, and gave much encouragement to individual workers at this fruitful period in the use of the instrument in histology. A meeting, held in his house in 1839, resulted in the foundation of the Microscopical Society of London (later the Royal Microscopical Society). The Quekett Microscopical Club was named in his honour.