Equipment used for continuous fermentation

Collection of equipment used for continuous fermentation at the Microbiological Research Establishment, Porton Down

Continuous fermentation lets scientists grow large batches of bacteria for research or industrial purposes. Carefully controlled conditions allow the bacteria to grow quickly in a culture medium which contains the nutrients they need to thrive. This continuous fermentation apparatus was used at the Microbiological Research Establishment at Porton Down, the UK government’s research facility for biological and chemical defence.

Much of this equipment was specially designed by scientists at Porton Down, including the ‘Porton pot’. This flask was designed to stop harmful bacteria from leaking into the laboratory, or unwanted bacteria from getting into the equipment. The many valves and tubes attached to the flask allowed the fermentation process to be strictly controlled, so scientists could study only the bacteria they needed.

Interest in chemical and biological warfare began in earnest during the First World War, when both sides infamously used mustard gas on the battlefield. In the 1930s, as war with Germany began to look more likely, the British government increased funding for research into chemical and biological weaponry and defence. These were never used, and after the war the UK’s focus shifted purely to defending its civilian and military populations against attacks, while much of its research had industrial and medical applications outside its original military context.

Today, chemical and biological weapons are banned by international law, and the UK’s old supplies have been destroyed. The UK government still conducts defence research at Porton Down, at what is now the Defence Science and Technology Laboratory.

Continuous fermentation rig, comprising two dexion frames as supporting structures for equipment used for continuous fermentation, used at the Microbiological Research Establishment, Porton Down, late 1950s

Continuous fermentation rig

1956-1959

Control unit for continuous fermentation equipment, designed and used at the Microbiological Research Establishment, Porton Down, early 1960s.

Control unit

1960-1969

Laboratory glassware

Laboratory glassware

Foam catchpot, part of continuous fermentation equipment used at the Microbiological Research Establishment, Porton Down, consisting of a glass vessel, slightly flared at either end, with metal stoppers at both ends, containing off-white textile filling. The metal stoppers incorporate fine metal tubes for attaching to rubber tubes. The vessel is attached by rubber tubes to /5, growth beaker

Foam catchpot

Growth breaker attached to drip counter, part of continuous fermentation equipment, attached to drip counter used at the Microbiological Research Establishment, Porton Down, consisting of a cylindrical glass vessel with stoppers at both ends, which incorporate fine metal tubes to attach to rubber tubes. Stoppers attached at both ends by metal bars clamped to the vessel by black poles secured with wingnuts. Protruding from the bottom of the vessel are two connections to tubes: one leads to a fine glass drip counter, the other attaches the vessel to /4, foam catchpot

Growth breaker

Metal filter with condenser attached to rubber tubes, part of continuous fermentation equipment, bolted to 1984-492/1/1 dexion rig with four wingnuts, used at the Microbiological Research Establishment, Porton Down

Filter with condenser

Two motorised pumps, part of continuous fermentation equipment used at Microbiological Research Establishment, Porton Down

Two motorised pumps

3l ‘Porton pot’ used for continuous fermentation at the Microbiological Research Establishment, Porton Down dating from early to mid 1950s, comprising a clear glass vessel with spout towards the bottom, stoppered with a bung. Circular metal rings at the top and bottom are connected with thin metal columns secured on top with nuts. Rubber tubes are connected to the top of the vessel and inside is a stirring device comprising a single length of metal suspended in the centre of the flask bent in a tear-shaped loop at the bottom

‘Porton pot’ laboratory glassware

1950-1955

Brass filter devised for continuous fermentation at the Microbiological Research Establishment, Porton Down, comprising a metal cylinder with metal spouts at either end attached to rubber tubes that connect to a glass tube from one end and a metal tube at the other. The whole assembly is attached to 1984-492/1/1, dexion rig

Brass filter

Universal Marconi Instruments Universal Bridge TF1313A for the Microbiological Research Establishment, Porton Down, comprising a grey box of electrical equipment with dials and switches

Universal Bridge

Details

Category:
Biotechnology
Object Number:
1984-492
type:
continuous fermentation apparatus
credit:
Centre for Applied Microbiology