Molecular model showing the structure of insulin

Made:
1967 in England
maker:
Dorothy Mary Crowfoot Hodgkin

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Science Museum Group Collection
© The Board of Trustees of the Science Museum

Science Museum Group Collection
© The Board of Trustees of the Science Museum

Science Museum Group Collection
© The Board of Trustees of the Science Museum

Model, one of two, made by Dorothy M. Crowfoot Hodgkin c.1967, to show the structure of 2 zinc pig insulin crystals at a resolution of 2.8A

In 1935, Dorothy M Crowfoot Hodgkin (1910-94), a British chemist and crystallographer, published the first X-ray photograph of insulin. Insulin is produced by the pancreas to break down sugars in the body. But Hodgkin and her team were unable to determine the 3-D structure of insulin until 1969, when this model was made. The larger metal balls in the model represent zinc, which was introduced chemically into the protein to decode the rest.

Details

Category:
Biotechnology
Object Number:
1991-286/1
Materials:
copper alloy, plastic and steel
type:
molecular model
taxonomy:
  • visual and verbal communication
  • model - representation
credit:
Prof. Dorothy Crowfoot Hodgkin